> [!tldr] An auto-immune disease that sucks. [^1] An autoimmune disorder that primarily affects the spine and pelvis affecting 0.1% to 0.8% of people. Men and women likely get the disease about equally often, but it’s usually worse in men. It's onset is usually in people’s 20s, typically felt in the low-back/buttock region. Heavily correlated with the HLA-B27 antigen. About 85% of people with AS have HLA-B27. We don't know why. # Measurement Bath Ankylosing Spondylitis Functional Index (BASFI) ## Treatment High powered NSAIDs TNF Inhibitors. ## Related Conditions uveitis/iritis inflammation of the heart inflammatory bowel disease inflammation of the knees, ankles, and feet **** ## Source - Personal experience, unfortunately. - [Ankylosing spondylitis - Wikipedia](https://en.wikipedia.org/wiki/Ankylosing_spondylitis) ## Related - [[Inflammation]] - [[Anti-inflammatory Drugs]] - [[Immune System]] [^1]: You know, not like those fun ones you hear about